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For those with more severe deficiencies or absorption problems, B12 injections may be prescribed

NICE Clinical Knowledge Summaries recommend B12 injections for: Pernicious anaemia an autoimmune condition affecting intrinsic factor production Malabsorption syndromes including coeliac disease and inflammatory bowel disease Post-surgical states particularly following gastrectomy or ileal resection Strict vegan diets when oral supplementation proves inadequate, though oral cyanocobalamin is usually sufficient for dietary deficiency Clinical trials demonstrate that B12 injections rapidly improve haematological parameters and neurological symptoms when deficiency is confirmed through blood tests

You may feel a slight sting or burn when administering the injection, but it varies from person-to-person

Severe organ dysfunction (kidney or liver failure) might slow peptide clearance and is screened for